Expanded Bed Adsorption (XPure-E)

Personal information


XPure Systems



Service Provider:

XPure Systems

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Type of Collaboration:Fee paying basisFunded collaborative projectJoint venturesNegotiable
What "non-technical" services relevant to scale-up does your organisation offer?:Process ModellingTechnoeconomic Assessment


Asset Information:
Expanded Bed Adsorption (XPure-E)
Raw Material:
Biomass - any
Process Stage:
Separation Technologies
Technology Area:
Physicochemical separations
Semi Pilot, Pilot, Demonstration
Additional Technical Information:
EBA chromatography effectively addresses the critical challenges of packed bed chromatography. It reduces e.g. clarification operations prior to the columns resulting in lower costs and improved yield. Minimal back pressure enables to achieve optimal scale of operation and productivity. The XPure-E system has been designed and built to perform EBA chromatography operation in a smooth and controlled fashion enabling:

Process development with enhanced scalability and operability
Handling viscous and turbid feed streams which are difficult to process through membranes or packed beds
Removal of clarifications steps prior to adsorption
5-15 % increase in product yield
2-4 x increase in productivity
10-20 % reduction in waste
In-situ product removal and cell recycling (fermentation based streams)
Address : Schipholweg 73-752316ZL NL

52.1682397, 4.4868181